听力与言语-语言病理学

行为科学

医学伦理学

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  • Y-chromosomal STR haplotypes and their applications to forensic and population studies in east Asia.

    abstract::We have analyzed 11 Y-STR loci (DYS19, the two DYS385 loci, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DXYS156Y) in 700 males from ten ethnic groups in east Asia in order to evaluate their usefulness for forensic and population genetic studies. A total of 644 different haplotypes were identified, among which ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0518-4

    authors: Kwak KD,Jin HJ,Shin DJ,Kim JM,Roewer L,Krawczak M,Tyler-Smith C,Kim W

    更新日期:2005-07-01 00:00:00

  • Racemization in enamel among different types of teeth from the same individual.

    abstract::We measured the quantity of D-aspartic acid (degree of racemization of aspartic acid) in the enamel of different types of teeth from the same individual. We studied the correlation between the degree of racemization and the time of formation of each particular tooth, as well as the applicability of the degree of racem...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0506-8

    authors: Ohtani S,Ito R,Arany S,Yamamoto T

    更新日期:2005-03-01 00:00:00

  • Quantification of secondary dentine formation from orthopantomograms--a contribution to forensic age estimation methods in adults.

    abstract::The accuracy of most age determination methods in adults is unsatisfactory and therefore more precise methods are required. Teeth provide several useful points about an individuals age. With advancing age secondary dentine is deposited along the wall of the dental pulp chamber leading to a reduction in the size of the...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0492-x

    authors: Paewinsky E,Pfeiffer H,Brinkmann B

    更新日期:2005-01-01 00:00:00

  • Cuts to the offender's own hand--unintentional self-infliction in the course of knife attacks.

    abstract::In a knife attack the perpetrator can unintentionally injure his own hand, if the knife does not have an adequate handguard and the tip of the blade hits a solid, mostly bony structure while being violently thrust into the victim's body. The injuries occurring under these conditions are localized on the flexor side of...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0491-y

    authors: Schmidt U,Faller-Marquardt M,Tatschner T,Walter K,Pollak S

    更新日期:2004-12-01 00:00:00

  • A proposed nomenclature for 15 canine-specific polymorphic STR loci for forensic purposes.

    abstract::We performed a population study on 15 polymorphic STR loci (FH2010, FH2079, PEZ2, VWF.X, FH2054, FH2087Ub, FH2611, WILMS-TF, PEZ12, PEZ15, PEZ6, FH2087Ua, ZUBECA4, ZUBECA6, FH2132) on 131 randomly selected dogs. Alleles were identified and grouped according to their estimated fragment length using fixed allelic bins e...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0452-5

    authors: Eichmann C,Berger B,Parson W

    更新日期:2004-10-01 00:00:00

  • Sudden cardiac death in hereditary hemochromatosis: an underestimated cause of death?

    abstract::Hereditary hemochromatosis (HH) is a frequent autosomal recessive disease which causes iron-overload of various organs. Of all northern European affected individuals, 90-95% show 1 of 3 known point mutations in the HFE gene. Symptoms and organs involved can vary considerably: Only a small fraction of the 200,000-400,0...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0451-6

    authors: Klintschar M,Stiller D

    更新日期:2004-06-01 00:00:00

  • Duplication of DYS19 flanking regions in other parts of the Y chromosome.

    abstract::During the testing of alternative primers for the Y chromosome short tandem repeat marker DYS19, a duplicated region of the Y chromosome was discovered. The duplicated sequence is contained within GenBank accession AC006335 and has a high degree of homology with the DYS19 flanking region (GenBank accession AC017019) b...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0436-5

    authors: Butler JM,Schoske R

    更新日期:2004-06-01 00:00:00

  • Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians.

    abstract::We have sequenced the entire mtDNA genome (mtGenome) of 241 individuals who match 1 of 18 common European Caucasian HV1/HV2 types, to identify sites that permit additional forensic discrimination. We found that over the entire mtGenome even individuals with the same HV1/HV2 type rarely match. Restricting attention to ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0427-6

    authors: Coble MD,Just RS,O'Callaghan JE,Letmanyi IH,Peterson CT,Irwin JA,Parsons TJ

    更新日期:2004-06-01 00:00:00

  • Mutations in 14 Y-STR loci among Japanese father-son haplotypes.

    abstract::In the present study 161 Japanese father/son haplotype transfers in 147 pedigrees were analyzed at 14 Y-STRs with two multiplex PCR-based typing systems. Five isolated single repeat mutations were identified at the DYS389I, DYS439, Y-GATA-H4, DYS389II and DYS391 loci, and a pedigree showing triple alleles at the DYS38...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0422-3

    authors: Kurihara R,Yamamoto T,Uchihi R,Li SL,Yoshimoto T,Ohtaki H,Kamiyama K,Katsumata Y

    更新日期:2004-06-01 00:00:00

  • Airbag contact in traffic accidents: DNA detection to determine the driver identity.

    abstract::A total of 34 deployed driver and passenger airbags from altogether 20 vehicles after frontal collisions were investigated. In 80% of the airbags possible biological traces could be located with an alternative light source (ALS, Polilight) at a wavelength of 450-470 nm. These traces were swabbed, a part of them additi...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0406-3

    authors: Grubwieser P,Pavlic M,Günther M,Rabl W

    更新日期:2004-02-01 00:00:00

  • Development of a 13-locus PCR multiplex system for paternity testing.

    abstract::In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0420-5

    authors: Schlenk J,Seidl S,Braunschweiger G,Betz P,Lederer T

    更新日期:2004-02-01 00:00:00

  • An easily automated, closed-tube forensic DNA extraction procedure using a thermostable proteinase.

    abstract::Most standard procedures for extracting DNA from forensic substrates involve manipulations that expose the sample to potential contamination and which reduce yields. Furthermore, most methods require centrifugation and/or solvent extraction steps that render them difficult to automate. We describe a simple closed-tube...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0400-9

    authors: Moss D,Harbison SA,Saul DJ

    更新日期:2003-12-01 00:00:00

  • Differences in the D/L aspartic acid ratios in dentin among different types of teeth from the same individual and estimated age.

    abstract::We have studied the correlation between the level of D-aspartic acid in dentin and the period of dentin formation in different types of teeth from the same individual. Except for the third molar, it is generally agreed that the formation of permanent dentin follows the pattern of growth, occurring earliest in the firs...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0365-8

    authors: Ohtani S,Ito R,Yamamoto T

    更新日期:2003-06-01 00:00:00

  • The Kaiser's tooth.

    abstract::The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...

    journal_title:International journal of legal medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s00414-002-0336-5

    authors: Pfeiffer H,Benthaus S,Rolf B,Brinkmann B

    更新日期:2003-04-01 00:00:00

  • Immunohistochemical localization of mast cells as a tool for the discrimination of vital and postmortem lesions.

    abstract::In wounds that are inflicted at least 60 min before death, histamine levels can increase up to 100%. This functional effect might have a morphometric counterpart. Mast cells play a crucial role in acute inflammatory reactions and in the healing process of wounds. Therefore, the density of these cells was immunohistoch...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-002-0304-0

    authors: Bonelli A,Bacci S,Vannelli B,Norelli A

    更新日期:2003-02-01 00:00:00

  • Molecular characterisation of the nucleic acids recovered from aged forensic samples.

    abstract::The molecular composition of the genetic substrate recovered from seven aged forensic samples has been extensively investigated. A simple enzymatic test based on DNAseI incubation of the extracts showed that the UV-fluorescent material from the forensic specimens is composed of nucleic acids, with the DNA fraction rep...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-002-0326-7

    authors: Previderè C,Micheletti P,Perossa R,Grignani P,Fattorini P

    更新日期:2002-12-01 00:00:00

  • First Polish DNA "manhunt"--an application of Y-chromosome STRs.

    abstract::This study presents the application of Y-chromosomal STR polymorphisms to male identification in the case of a serial rapist and woman murderer in Poland. Since August 1996 a rapist from Swinoujscie (northwest Poland) committed at least 14 rapes. In the year 2000 he brutally raped 8 young girls and murdered a 22-year-...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-002-0320-0

    authors: Dettlaff-Kakol A,Pawlowski R

    更新日期:2002-10-01 00:00:00

  • Distribution of kerosene components in rats following dermal exposure.

    abstract::The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-001-0282-7

    authors: Tsujino Y,Hieda Y,Kimura K,Eto H,Yakabe T,Takayama K,Dekio S

    更新日期:2002-08-01 00:00:00

  • Purification of STR-multiplex-amplified microsamples can enhance signal intensity in capillary electrophoresis.

    abstract::In this study, the effect of sample purification on total signal intensities of samples amplified with genRES MPX-2 (nine-locus multiplex) prior to capillary electrophoretic analysis has been investigated. Sample purification with the Qiaquick PCR purification kit led to an increase of the relative fluorescent signal ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-001-0277-4

    authors: Lederer T,Braunschweiger G,Betz P,Seidl S

    更新日期:2002-06-01 00:00:00

  • Is the amelogenin gene reliable for gender identification in forensic casework and prenatal diagnosis?

    abstract::In humans, the amelogenin gene is present on both the X and the Y chromosomes. However, there are size differences in this gene between these chromosomes, which have been utilised for sexing in forensic casework and prenatal diagnosis. Our study using the AmpFl STR Profiler Plus kit, showed a deletion of Y chromosome-...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-001-0262-y

    authors: Thangaraj K,Reddy AG,Singh L

    更新日期:2002-04-01 00:00:00

  • Determination of firing distance using the rhodizonate staining technique.

    abstract::The histological staining technique using rhodizonate is also effective for the determination of the firing distance by examining the distribution and intensity of the staining reaction. The differentiation between absolute close-range shots and long-range shots is generally possible without any doubt. The method is n...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100220

    authors: Marty W,Sigrist T,Wyler D

    更新日期:2002-02-01 00:00:00

  • Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vitreous humour.

    abstract::Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently be...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100239

    authors: Bocaz-Beneventi G,Tagliaro F,Bortolotti F,Manetto G,Havel J

    更新日期:2002-02-01 00:00:00

  • A dangerous design for a mountain bike.

    abstract::The case of a man's death as a consequence of an accident with a mountain bike was examined. Despite only slight external injuries, a general examination revealed the existence of a rupture of the diaphragm which was the ultimate cause of death. The discussion reconstructs the way the accident occurred and briefly ana...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100237

    authors: Alvarez-Segui M,Castello-Ponce A,Verdu-Pascual F

    更新日期:2001-12-01 00:00:00

  • Sequence of melanocyte migration into human scar tissue.

    abstract::Scars of human skin can on occasions provide a very useful ancillary method of identification of an unknown deceased. If the age of any visible scars can be estimated objectively, then this might be of some assistance in the identification procedure. Melanocytes migrate into scar tissue as it ages and their number wit...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100225

    authors: Dressler J,Busuttil A,Koch R,Harrison DJ

    更新日期:2001-10-01 00:00:00

  • VWA STR genotyping: further inconsistencies between Perkin-Elmer and Promega kits.

    abstract::We report a simultaneous study of the VWA STR locus by the Perkin-Elmer Profiler Plus kit and the Promega GenePrint CTTv kit in a population sample from North Portugal and in 418 meiosis from family material and paternity cases. PCR amplification and genotyping were performed according to the manufacturer's instructio...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100215

    authors: Alves C,Amorim A,Gusmão L,Pereira L

    更新日期:2001-10-01 00:00:00

  • Identification and characterization of two novel human polymorphic STRs on the Y chromosome.

    abstract::From sequence database information, we have identified two male-specific and polymorphic tetranucleotide STRs, DYS 441 (GDB:10013873) and DYS 442 (GDB: 10030304), on the Y chromosome. Analysis of 184 males allowed 7 and 5 alleles to be distinguished in the DYS 441 and DYS 442 systems, respectively, yielding 21 haploty...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100207

    authors: Iida R,Tsubota E,Matsuki T

    更新日期:2001-08-01 00:00:00

  • The evidential value of STRs. An analysis of exclusion cases.

    abstract::In this study, a total of 191 cases with STR exclusions out of 591 paternity cases were analysed using 2 STR sets, i.e. (set a) 5 STRs in 462 cases with 150 exclusions and (set b) 9 STRs in 129 cases with 41 exclusions. Set (a) was associated with four exclusions on average while set (b) showed five exclusionary loci ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140000174

    authors: Brinkmann B,Pfeiffer H,Schürenkamp M,Hohoff C

    更新日期:2001-01-01 00:00:00

  • Trajectory reconstruction from trace evidence on spent bullets. II. Are tissue deposits eliminated by subsequent impacts?

    abstract::STR-based individualisation of biological deposits on bullets after perforation of tissue, can identify the person injured or killed by a particular bullet and comparison with the firearms used can identify the weapon and thus possibly the person who did the shooting. In this study, the effect of subsequent impacts on...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140000203

    authors: Karger B,Stehmann B,Hohoff C,Brinkmann B

    更新日期:2001-01-01 00:00:00

  • MtDNA control region and RFLP data for Sicily and France.

    abstract::The forensic application of mtDNA typing requires large databases which are regionally well defined. To further this aim, we have typed mtDNA in a sample of 111 French and 106 Sicilians. The French were typed for both hypervariable segments (HVR1 and HVR2) of the mtDNA control region, whereas the Sicilians were only t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140000169

    authors: Cali F,Le Roux MG,D'Anna R,Flugy A,De Leo G,Chiavetta V,Ayala GF,Romano V

    更新日期:2001-01-01 00:00:00

  • A novel dimorphism in the human SRY gene: usefulness in human migration studies.

    abstract::A nucleotide polymorphism of C or T was detected at position 465 in the sex-determining region Y (SRY) gene. To evaluate the utility of this dimorphism in human population studies, the frequency and the frequency of the haplotype combined with the two polymorphic loci YAP and M9 were examined in a total of 130 unrelat...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004149900111

    authors: Naito E,Umetsu K,Yuasa I,Dewa K,Sumi H,Yamanouchi H

    更新日期:2001-01-01 00:00:00

  • Mitochondrial DNA sequences for 118 individuals from northeastern Spain.

    abstract::A population database was generated from 118 unrelated Caucasoid individuals living in Spain. Sequence polymorphisms of the mitochondrial DNA (mtDNA) control region, hypervariable regions I and II (HVRI and HVRII) were determined using the polymerase chain reaction (PCR) and direct sequencing. A total of 102 different...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140000158

    authors: Crespillo M,Luque JA,Paredes M,Fernández R,Ramírez E,Valverde JL

    更新日期:2000-01-01 00:00:00

  • Diatom detection in the diagnosis of death by drowning.

    abstract::A medicolegal/algological collaboration lasting several years aimed at developing methods for dealing with dead bodies found in water where the circumstances are not clear, has led to an interdisciplinary procedure. To enable algological analysis, sample preservation and preparation must be free from contamination or ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s004149900122

    authors: Hürlimann J,Feer P,Elber F,Niederberger K,Dirnhofer R,Wyler D

    更新日期:2000-01-01 00:00:00

  • Deaths associated with MBDB misuse.

    abstract::The use of phenethylamines in the dance scene is now well established. Apart from amphetamine, the commonest phenethylamine encountered in clinical and forensic settings is 3,4-methylenedioxymethamphetamine (MDMA) commonly known as ecstasy. Other phenethylamines, which have similar effects are encountered, such as 3,4...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050291

    authors: Carter N,Rutty GN,Milroy CM,Forrest AR

    更新日期:2000-01-01 00:00:00

  • The application of dental methods of identification to human burn victims in a mass disaster.

    abstract::This paper deals with the usefulness of dental identification in the case of 28 human burn victims of a bus accident in Spain. Postmortem forensic procedures for identification were used including general external examination, routine photographs and radiographs and complementary biological methods. Dental identificat...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004149900099

    authors: Valenzuela A,Martin-de las Heras S,Marques T,Exposito N,Bohoyo JM

    更新日期:2000-01-01 00:00:00

  • Genetic variability at nine STR loci in the Chueta (Majorcan Jews) and the Balearic populations investigated by a single multiplex reaction.

    abstract::A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004149900101

    authors: Tomàs C,Picornell A,Castro JA,Ramon MM,Gusmão L,Lareu MV,Carracedo A

    更新日期:2000-01-01 00:00:00

  • Further sequence and length variation at the STR loci HumFES/FPS, HumVWA, HumFGA and D12S391.

    abstract::This paper reports population data and statistics for the HumFES/FPS, HumVWA, HumFGA and D12S391 loci in Austria. The sequences of some rare and new variant alleles which have been identified in the course of the present population study and other investigations are described. Sequence variation occurred in a HumFES/F...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/pl00007712

    authors: Dauber EM,Glock B,Schwartz DW,Mayr WR

    更新日期:2000-01-01 00:00:00

  • Stability of carbohydrate deficient transferrin (CDT) in stored blood samples.

    abstract::The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050013

    authors: Köhler H,West A,Brinkmann B

    更新日期:2000-01-01 00:00:00

  • Gunshot wound to the head with full recovery.

    abstract::A 28-year-old man was shot in the back of the head at close range by a robber who then locked him in a room assuming that he was dead. The man was discovered 2 days later. The entrance wound of the bullet was in the left occipital region and it passed into the periphery of the right temporal lobe, where it lodged. The...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004149900120

    authors: Rothschild MA,Schneider V

    更新日期:2000-01-01 00:00:00

  • Proficiency testing for psychoactive substances in Italy.

    abstract::This paper describes the general design and main results of the Italian proficiency testing program for the analysis of psychoactive substances in urine, a long-term initiative created in 1995 on an educational basis and characterized by an innovative internet-based service for data exchange between laboratories and t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050279

    authors: Ferrara SD,Brusini G,Maietti S,Frison G,Castagna F,Allevi S,Menegus AM,Tedeschi L

    更新日期:1999-01-01 00:00:00

  • Biostatistical evaluation of mixed stains with contributors of different ethnic origin.

    abstract::The analysis of a mixed biological stain by means of highly polymorphic VNTR systems usually reveals a profile composed of multiple alleles. If the victim and one or several suspects match the profile the evidential strength of the matches has to be very carefully analysed. The appropriate methods for the statistical ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050019

    authors: Fukshansky N,Bär W

    更新日期:1999-01-01 00:00:00

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